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SoftWave Research

Newest Research

Click to access Science Compendium List 2024_02_02
European Heart Journal
Sticky Post

SoftWave TRT Affiliate Study Featured in Prominent Medical Journal

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Elucidating the molecular mechanisms underlying cardiac shock wave therapy

Zimmer enPulsPro Shockwave Machines-

Shockwave Therapy for Chiropractors: Complete Guide

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

Current concepts of shockwave therapy in stress fractures

Extracorporeal shock wave therapy surpresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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Extracorporeal Shock Wave Treatment: An Emerging Treatment Modality For Retracting Scars of The Hands

Pulsewave Therapy- Mechanism of Action and Clinical Indications

Pulsewave Therapy Explained: Mechanism of Action and Clinical Indications

StemWave vs. SoftWave: Which Shockwave Machine Should You Buy for Your Chiropractic Practice?

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Extracorporeal shock wave therapy for the treatment of coccydynia: a series of 23 cases

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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s Disease – A New Navigated Focal Brain Therapy

Using Sound to Battle Opioid Crisis

Effect of shockwave therapy on orthodontic tooth movement

EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

Gainswave Machines: Cost, Efficacy, & Alternatives

SoftWave vs. GainsWave Therapy for ED and Beyond

Radial Shockwave Therapy Machines Compared 

The Physics of Shock Wave Lithotripsy

Indications for shockwaves in veterinary medicine

How to Manage Pain Without Drugs

Effects of Shock Waves on Expression of IL-6, IL-8, MCP-1, and TNF- alpha Expression by Human Periodontal Ligament Fibroblasts: An In Vitro Study

Urological Times Cover – Scroll to Page 18 – 19

SoftWave TRT vs Storz Shockwave Machines Compared

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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Extracorporeal shockwave therapy induces alveolar bone regeneration

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Stromal Vascular Fraction Combined with Shock Wave for the Treatment of Peyronie’s Disease

Best Treatment for Tennis Elbow Relief

Extracorporeal shock wave therapy (ESWT) in urology:a systematic review of outcome in Peyronie’s disease, erectile dysfunction and chronic pelvic pain

Extracorporeal shockwave therapy (ESWT) in the treatment of atrophic non-unions of femoral shaft fractures

miR-19a-3p Containing Exosomes Improve Function of Ischaemic Myocardium Upon Shock Wave Therapy

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​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease

Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

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The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

Cellulite and Focused Extracorporeal Shockwave Therapy for Non-Invasive Body Contouring: A Randomized Trial

Best Medical Devices for Treating Achilles Tendinitis

Best Medical Devices for Treating Achilles Tendinitis

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

ESWT minimizes ischemic tissue necrosis…

ESWT Therapy for Treatment of Keloid Scars

ESWT for retracting scars of the hand

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia vi a Toll-like receptor 3 dependent mechanism

Chronic Tendonitis Treatment When Injections Have Failed

Chronic Tendonitis Treatment When Injections Have Failed

Stem cells pose risk, offer promise

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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7 Red Flags That Signal a Risky Shockwave Device

Can Shockwave Therapy Cause Damage?

Shock waves promote spinal cord repair via TLR32

Shockwave therapy in stress fractures

Acoustic wave therapy for cellulite, body shaping and fat reduction.

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Physical Rehabilitation Using Shockwave Therapy

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Shockwave Therapy as First-Line Treatment for Peyronie’s Disease: A Prospective Study

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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SoftWave Therapy Averts Amputation for Former College Football Coach

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​Shockwaves induce osteogenic differentiation of human mesenchymal stem cells through ATP release and activation of P2X7 receptors

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Extracorporeal Shock Wave Therapy in Peyronie’s Disease: Clinical Efficacy and Safety from a Single-Arm Observational Study

TISSUE REGENERATION TECHNOLOGIES, LLC Establishment Registration & Device Listing

Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-β1

Regenerative Restorative Care Treatments Post Knee Surgery

Regenerative Restorative Care Treatments Post Knee Surgery

Improvement of adipose tissue–derived cells by low-energy extracorporeal shock wave therapy

Is Shockwave Therapy Painful? What Practice Owners Should Tell Patients

The Biologic Effects of SoftWaves™and Rationale for Spine and Brain Therapy

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The efficacy of ultrasound-guided extracorporeal shockwave therapy in patients with cervical spondylosis and nuchal ligament calcification

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Patient consulting a doctor about finding a shockwave therapy provider for sports injuries.

Find a Shockwave Therapy Provider for Sports Injuries

The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat

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Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

What Doctors Should Know About Storz Medical Shockwave

Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice

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ESWT affects Schwann cell phenotype in vitro and in vivo thereby accelerating nerve regeneration

​Prospective randomized phase II trial of accelerated reepithelialization

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite e A current metaanalysis​ -(Plastic, Hand and Burn Surgery, University of Schlewig Holstein, Lubeck, Germany​)

First Report for Unfocused Low Intensity SoftWave® Therapy (uESWT ) for Nocturia and Erectile Dysfunction (ED)

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

AUVA letter‒ Successful treatment of delayed and non-union fractures

ESWT for resident stress fractures in athletes.

Exploring Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Regenerative Shoulder Treatment for Rotator Cuff and Overuse Injuries

Zapping chronic tendon pain

Early angiogenic response to shock waves in a three-dimensional model of human microvascular endothelial cell culture (HMEC-1)

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

​STORZ MEDICAL’s NEUROLITH® receives CE approval – Transcranial Pulse Stimulation (TPS) on the central nervous system of patients with Alzheimer’s disease

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​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

Government Sales

What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

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​Extracorporeal shock wave therapy: What? Why? Safety?

Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

Spark Wave® Therapy Improves Full Thickness Skin Defects

Expanding Non-Surgical Options in Podiatry Clinics

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Shockwave Therapy Of The Heart​

Alternatives to Cortisone Shots for Joint Pain Relief

Alternatives to Cortisone Shots for Joint Pain Relief

7 Red Flags That Signal a Risky Shockwave Device

Shockwave Therapy for Physical Therapists

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy

Effective Medical Devices for Treating Uterine Fibroids

Effective Medical Devices for Treating Uterine Fibroids

Physical therapist guiding a woman through a leg exercise for sciatica pain.

Physical Therapy Treatment for Sciatica Pain: A Guide

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

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Alternatives to Surgery

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Is it possible to change of the duration of consolidation period in the distraction osteogenesis with the repetition of extracorporeal shock waves?

Storz Duolith Machines- Cost, Efficacy, & Alternatives

Storz Duolith Machines Compared

Extracorporeal shock wave therapy: clinical applications and regulation

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

LL37 and shock waves

Comparing Shockwave Technologies for Treating Diabetic Foot Ulcers

The Use of Shock Waves in Peripheral Nerve Regeneration:New Perspectives?

What Is Pulse Wave Therapy & Does It Work for Patients?

What Is Pulse Wave Therapy & Does It Work for Patients?

Lithotripter outcomes in a community practice setting: Comparison of an electromagnetic and an electrohydraulic lithotripter

Low–Energy Shockwave Therapy Improves Ischemic Kidney Microcirculation

Low Intensity Extracorporeal Shock Wave Therapy Improves Erectile Function in a Model of Type II Diabetes Independently of NO/cGMP Pathway

StemWave Machine: Cost, Reviews & Alternatives for Practice Owners

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Erectile Dysfunction before and after results under ultrasound

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

Effectiveness of shock wave therapy: implementation of a soft wide focus applicator in patients with erectile dysfunction

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Three-time Super Bowl Champ RandyCross Finds Pain Relief With InnovativeTherapy from SoftWave TRT

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Transcranial Pulse Stimulation with Ultrasound in Alzheimer’s disease

SoftWave vs Shockwave Technology Explained 

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Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Extracorporeal shockwave treatment for chronic diabetic foot ulcers

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CM Shockwave Before And After Use

COVID-19 pneumonia: different respiratory treatment for different phenotypes?

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin Angiotensin System

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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Peyronie’s disease and low intensity shock wave therapy: Clinical outcomes and patient satisfaction rate in an open-label single arm prospective study in Australian men

Extracorporeal shockwave: mechanisms of action and physiological aspects…

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and aging

Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

Effect of shock waves on macrophages

Best Medical Devices for Treating Carpal Tunnel Syndrome

Best Medical Devices for Treating Carpal Tunnel Syndrome

Linear Shockwave Therapy in Clinical Practice- Evidence and Mechanisms

Linear Shockwave Therapy Mechanisms and Efficacy Explained

Shock wave therapy for systemic sclerosis

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SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

Shock Wave Therapy Compared with Intramedullary Screw Fixation for Nonunion of Proximal Fifth Metatarsal Metaphyseal-Diaphyseal Fractures

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Project: SoftWaves to prevent opioid addiction and to help addicts in their recovery.

Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

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EPAT Therapy for Plantar Fasciitis vs Alternatives

Cellular mechanotransduction: putting all the pieces together again

Peripheral Nerve Regeneration

Peripheral Nerve Regeneration

MTS Science White Paper – Softwave – Pain Therapy

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

Can cellulite be treated with low-energy extracorporeal shock wave therapy?

Medispec Shockwave Devices- Efficacy & Alternatives

Medispec Shockwave Devices: Efficacy & Alternatives

​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

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The Role of Shockwaves in the Enhancement of Bone Repair – From Basic Principles to Clinical Application

Shock Waves Reach Dental Implantology (Spanish)

IVSWT Water Bath V2.0 Manual

Set up Instructions

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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

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Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Acoustic Field of a Ballistic Shock Wave Therapy Device

Traditional Reimbursement vs Hybrid Practice for Shockwave Providers

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

Mesenchymal stem cells: Myths and reality

The link between shockwaves and innate immunity – the main working mechanism?

Best Medical Devices for Treating Patellar Tendinitis

Best Medical Devices for Treating Patellar Tendinitis

Technology Assessment “Wound Care” dermagold100

Effects of Low-Energy Shock Waves on Oral Bacteria

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What Is StemWave Therapy? How It Works, What It Costs & How It Compares

Biological mechanism of musculoskeletal shockwaves

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Ultrasound Brain Stimulation Piloted in Alzheimer Study

Comparing Shockwave Therapy Machine Costs

Shockwave + Biologic Regeneration: Two Paths to Healing, One Goal

How to Improve Podiatry Practice ROI

Review of the Current Status of Low Intensity Extracorporeal Shockwave Therapy (Li-ESWT) in Erectile Dysfunction (ED)

​Therapeutic effects of Low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence

Impact of extracorporeal shock wave therapy (ESWT) on orthodontic tooth movement-a randomized clinical trial.

Purple Heart Recipient Uses Innovative Technology to Treat Fellow Veterans

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Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

Is SoftWave Therapy for Home Use?

Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Minimally invasive treatment of Peyronie’s disease: evidence-based progress

Best Shockwave Machine for Providers

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The influence of comorbidities – ESWT for chronic soft tissue wounds

The Effect of Different Doses of Extracorporeal Shock Waves on Experimental Model Mandibular Distraction

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

Shockwave Therapy for Achilles Tendonitis

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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