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Newest Research

Click to access Science Compendium List 2024_02_02

Spark Wave® Therapy Ameliorates Urinary Incontinence

DIGEST Guidelines for Extracorporeal Shock Wave Therapy

What Doctors Should Know About Storz Medical Shockwave

Limited shock wave therapy vs sham treatment in men with Peyronie’s disease: results of a prospective randomized controlled double-blind trial

Focused Shockwave Therapy Efficacy & Alternatives

Focused Shockwave Therapy Efficacy & Alternatives

Angiogenic response upon shock wave treatment of the ischaemic muscle

SDSM Spine pain protocol

Effects of Low-Energy Shock Waves on Oral Bacteria

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Extracorporeal shock waves, a new non-surgical method to treat severe burns

Extrakoprorale Stoßwellentherapie am Knochen – Voodoo oder Therapieoption?

Clinical evidence of SparkWave™ therapy in the treatment of erectile dysfunction

Extracorporeal shockwave therapy (ESWT) e First choice treatment of fracture non-unions?

​Spark Waves® in Neurodegenerative Diseases – Concept for the Treatment of Alzheimer’s and Parkinson’s Disease

ISMST (International Society for Medical Shockwave Treatment)

​Antibacterial effects of extracorporeal shock waves

Low-intensity extracorporeal shock wave therapy for erectile dysfunction after radical prostatectomy

Neuropathy

Shockwave Therapy for Neuropathy

Effect of Extracorporeal Shockwave Therapy (ESWT) on Pulpal Blood Flow After Orthodontic Treatment: A Randomized Clinical Trial

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Penile low intensity shock wave therapy for PDE5i non-responders suffering from vasculogenic Erectile Dysfunction since 2 to 10 years: A prospective, randomized, placebo-controlled study

Zimmer enPulsPro Shockwave Machines-

Zimmer enPulsPro Shockwave Machines: Efficacy & Alternatives

Clinical Outcomes of Extracorporeal Shock Wave Therapy in Patients With Secondary Lymphedema: A Pilot Study

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Placebo controlled, prospectively randomized, double-blinded study for the investigation of the effectiveness and safety of the acoustic wave therapy (AWT(®)) for cellulite treatment.

FUNDAMENTALS OF VIBRATION-INDUCED, CELL POLARIZING TREATMENT MALIGNER DISEASES

Defining a Therapeutic Range for Regeneration of Ischemic Myocardium via Shock Waves

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Top Surgeon: SoftWave ‘a superior way to make tissue want to heal’

Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptomes in a first-in-man trial

Technology Assessment “Wound Care” dermagold100

Acoustic wave therapy for cellulite, body shaping and fat reduction.

MTS Science White Paper – Softwave – Mesenchymal Stem Cell Therapy

Shock waves activate in vitro cultured progenitors and precursors of cardiac cell lineages from the human heart

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Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model

Chattanooga Intelect Shockwave Machine- Evidence, Mechanisms, and Clinical Context

Chattanooga Intelect Shockwave Machine: Efficacy & Alternatives

Extracorporeal shock wave therapy relieved pain in patients with coccydynia: a report of two cases

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Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

Shockwave treatment enhances cell proliferation and improves wound healing

2025 AUA Guidelines on Male Chronic Pelvic Pain: Shockwave Therapy Evidence and Clinical Implications

Renova Shockwave Therapy- What Is It & Does It Work for Patients?

Renova Shockwave Therapy: What Is It & Does It Work for Patients?

Shockwave Therapy Contraindications- When Not to Use It

Shockwave Therapy Contraindications: When Not to Use It

A randomized, controlled clinical study to investigate the safety and efficacy of acoustic wave therapy in body contouring

Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment

Low-energy shock waves treatment induces angiogenesis in ischemic muscle by stimulation of Toll-like receptor 3 signalling

Extracorporeal shock wave therapy (ESWT) for the treatment of spasticity in persons with spinal cord injury

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Lohse – Busch ISMST Presentation

SoftWave Tissue Regeneration Technologies Receives FDA Clearance for Blood Circulation Increase, Minor Aches and Pains Relief and Connective Tissue Activation

Influence of extracorporeal shock wave therapy (ESWT) on bone turnover markers in organisms with normal and low bone mineral density during fracture healing: a randomized clinical trial

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Letter regarding non unions in Europe. Dr. Schaden managing Director of the Workman’s Compensation Insurance Organization in Austria

Elucidating the molecular mechanisms underlying cardiac shock wave therapy

MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury

SoftWave on Elbow

Why Chiropractors Choose Shockwave Therapy

A study to identify the potential effects of extracorporeal shockwave therapy alone and in combination with Avastin.

Softwave application on hand

Healing at the Edge of the World: How Dr. Paul Kratka Brings SoftWave to the South Pacific

Extracorporeal shockwave therapy as supplemental therapy for closure of large full thickness defects – Rat full -thickness skin graft model

Biological Principles – Mechanotransduction

Low Intensity Shock Wave Therapy: Regenerative Therapy for Erectile Dysfunction

Shock wave therapy enhances neuronal sprouting and improves neuronal survival

Scientific Reports – Gene transfection by shock waves

Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain syndrome of the trapezius.

Effective Medical Devices for Temporomandibular Joint Dysfunction

Effective Medical Devices for Temporomandibular Joint Dysfunction

“In vitro” and multicolor phenotypic characterization of cell subpopulations identified in fresh human adipose tissue stromal vascular fraction and in the derived mesenchymal stem cells

Acoustic stimulation and tropism on skeletal muscles: Tissue resilience & regeneration in sports and ageing

Veterinary wound care case study

Latest Basic Research Abstracts

Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo

Using Sound to Battle Opioid Crisis

ESWT for Acute and Chronic Soft Tissue Wounds

Comparative SWT Data to Evaluate Competing Technologies in the Treatment of Penile Connective Tissue for Improved Erectile Function

Ultrasound Brain Stimulation Piloted in Alzheimer Study

Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus

Pilot Trial, First Report Worldwide for Unfocused SoftWave® Therapy (uESWT) for the Treatment of Testicles to Improve Testicular Size and Function

The Roll of Spark Waves in the Management of Chronic Wounds.

The link between shockwaves and innate immunity – the main working mechanism?

EPAT Therapy for Plantar Fasciitis vs Alternatives

Traditional Reimbursement vs Hybrid Practice for Shockwave Providers

The Applied Mechanical Vibration as Extracorporeal Shock Wave

Erectile Dysfunction before and after results under ultrasound

Alternative Treatment using Shockwave for Erectile Dysfunction

Zapping chronic tendon pain

Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture

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SoftWave Therapy Averts Amputation for Former College Football Coach

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Prof. M. Kravchik. Focused shockwave therapy in the treatment of the spine. Oxford, UK Non-invasive treatment of herniated discs by focused shock wave therapy

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Extracorporeal shock waves Improve pareses in 8 cases of spinal cord injury and 3 cases of myelomeningocele.

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​Update on the efficacy of extracorporeal shockwave treatment for myofascial pain syndrome and fibromyalgia

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Acoustic field characterization of the Duolith: Measurements and modeling of a clinical shock wave therapy device

The Role of Extracorporeal Shockwave Treatment in Musculoskeletal Disorders

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7 Red Flags That Signal a Risky Shockwave Device

7 Red Flags That Signal a Risky Shockwave Device

Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits

Biological mechanism of musculoskeletal shockwaves

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Effect of Electrohydraulic Extracorporeal Shockwave Therapy on the Repair of Bone Defects Grafted with Particulate Allografts

Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat—Systematic review

Shock wave therapy for osteoinduction

Three-Time Super Bowl Champion Randy Cross Discovers Pain Relief with SoftWave Therapy

Epicardial shock-wave therapy improves ventricular function in a porcine model of ischaemic heart disease.

Regenerative Skin Treatment for Burns, Scars, and Wounds

Regenerative Skin Treatment for Burns, Scars, and Wounds

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TRT SoftWaves® – a new regenerative therapy for paraplegia

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Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite

Impact of Extracorporeal Shock Wave Therapy (ESWT) on Orthodontic Tooth Movement – A Randomized Clinical Trial

The Physics of Shock Wave Lithotripsy

Regenerative Therapies for Hip Pain and Tendinopathy

Regenerative Therapies for Hip Pain and Tendinopathy

SoftWave TRT vs Storz Shockwave Machines Compared

Spark Wave® Therapy Improves Full Thickness Skin Defects

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

10 Questions Every Provider Should Ask Before Choosing a Shockwave Medical Device

Assessment of IL-1Beta and VEGF Concentration in Rat Model During Orthodontic Tooth Movement and Extracorporeal Shock Wave Therapy

Shock Wave Treatment Protects From Neuronal Degeneration via a Toll-Like Receptor 3 Dependent Mechanism: Implications of a First-Ever Causal Treatment for Ischemic Spinal Cord Injury

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Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study

Test12343

Body shaping with acoustic wave therapy AWT(®)/EPAT(®): randomized, controlled study on 14 subjects.

Urological Times Cover – Scroll to Page 18 – 19

Extracorporeal Acoustic Wave Therapy and Multiple Symmetric Lipomatosis

Alternatives to Orthopedic Surgery in Outpatient Rehab

Alternatives to Orthopedic Surgery in Outpatient Rehab

Extracorporeal shock wave therapy (ESWT) for wound healing: Technology, mechanisms, and clinical efficacy

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

Comparing Shockwave vs Injection-Based Regenerative Pain Treatments

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial

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Effect of unfocused extracorporeal shock wave therapy on growth factor gene expression in wounds and intact skin of horses. – PubMed – NCBI

A neural model for chronic pain and pain relief by extracorporeal shock wave treatment

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

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Linear Shockwave Therapy in Clinical Practice- Evidence and Mechanisms

Linear Shockwave Therapy Mechanisms and Efficacy Explained

Temporal and spatial expression of BMP-2 in sub-chondral bone of necrotic femoral heads in rabbits by use of extracorporeal shock waves

Non‑surgical Regenerative Treatments Integrating with PT

Non‑surgical Regenerative Treatments Integrating with PT

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Zimmer enPuls Shockwave Systems Compared and Explained for Clinical Practice

Zimmer enPuls Shockwave Machines Compared

Shockwave Therapy vs Therapeutic Ultrasound- Differences, Benefits, and Outcomes

Shockwave Therapy vs Therapeutic Ultrasound: Differences, Benefits, and Outcomes

Tissue Activation and Regeneration in Sports Medicine and Bone Pathologies

Analysis of extracorporeal shock wave therapy for Peyronie’s disease

Effect of penile rehabilitation with low intensity extracorporeal shock wave therapy

MTS Spark WavesTM – successfully treating indispositions of the musculoskeletal system

Treatment of scaphoid waist nonunion by one, two headless compression screws or plate with or without additional extracorporeal shockwave therapy

CM Shockwave Before And After Use

Doctor Uses Shockwave Therapy to Heal Nearly Severed Foot

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​The biologic effects of SoftWaves and rationale for spine and brain therapy

End-stage Heart Failure with COVID-19: Strong Evidence of Myocardial Injury by 2019-nCoV

Orthospec Shockwave System Clinical Uses, Evidence, and Limitations

Orthospec ESWT System Explained

Shock wave therapy for systemic sclerosis

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What Is HydroWave Therapy? Mechanism, Applications, and Clinical Context

What Is HydroWave Therapy? How It Works, Clinical Uses, and Evidence

Effects of ESWT on glycosaminoglycan expression during bone healing

Ultrasound Based Brain Stimulation

The Assessment of New Bone Formation Induced by Unfocused Extracorporeal Shock Wave Therapy Applied on Pre-Surgical Phase of Distraction Osteogenesis

Piezowave Shockwave Therapy vs Other Shockwave Devices

Piezowave Shockwave Therapy vs Other Shockwave Devices

EmFocus Shockwave Therapy- Features, Benefits, and Drawbacks

EmFocus Shockwave Therapy: Features, Benefits, and Drawbacks

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

Effect of shock waves on macrophages: A possible role in tissue regeneration and remodeling

Effect of Low-energy Extracorporeal Shock Waves on Orthodontic Tooth Movement and Miniscrew Stability

Molecular changes in diabetics foot ulcers

​Current research in this field is focused on shockwave therapy and on the role of inflammation and innaty immunity in myocardial infarction.

​Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy

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In vitro extracorporeal shock wave treatment has beneficial effects on rat Schwann cell isolation and culture

Shock wave treatment after hindlimb ischemia results in increased perfusion and M2 macrophage presence

MTS Spark Waves®– an effective therapy option for aesthetic indications Cellulite / Scars / Stretch marks / Lymphoedema / Alopecia -(MTS Science)

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: a single-center, randomized, placebo-controlled clinical trial.

Shockwave therapy in stress fractures

In Vitro Effects of Extracorporeal Shockwave Therapy (ESWT) on Proliferation and Metabolic Activity of Adult Human Keratinocytes

Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China

Unfocused extracorporeal shock wave therapy as potential treatment for osteoporosis

Effect of a Single Administration of Focused Extracorporeal Shock Wave in the Relief of Delayed-Onset Muscle Soreness: Results of a Partially Blinded Randomized Controlled Trial

​Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)

Effects of Extracorporeal Shock Wave Therapy on Spasticity in Patients after Brain Injury: A Meta-analysis

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Do Gymna Shockmaster Machines Work for Patients?

Do Gymna Shockmaster Machines Work for Patients?

MTS Spark WaveTM Technology and its mechanism of action in wound management

Low-energy extracorporeal shock wave therapy for a model of liver cirrhosis ameliorates liver fibrosis and liver function

Shockwave Therapy Of The Heart​

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

Expanding Non-Surgical Treatment Options for Meniscus Injuries in Clinical Practice

Test43212

SoftWave on Elbow

Radial Shockwave Therapy Benefits & Alternatives

Chattanooga Shockwave Devices Compared- What Clinicians Should Evaluate

Chattanooga Shockwave Therapy Devices Compared

Extracorporeal Shock Wave Device for Treatment of Chronic Burns

Analysis of treatment protocols: application of ESWT for wound healing disorders

Optimal timing of extracorporeal shock wave treatment to protect ischemic tissue

7 Red Flags That Signal a Risky Shockwave Device

Shockwave Therapy for Physical Therapists

Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis

Unfocused extracorporeal shock waves induce anabolic effects in rat bone

Regenerative Treatments for Athletes and Their Role Compared With Surgical Repair

Regenerative Treatments for Athletes Versus Surgical Repair

Effects of the extracorporeal shock wave therapy on the skin: an experimental study

Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers

OmniWave Shockwave Machines: Efficacy & Alternatives Explained

Benefits of Spark Wave Therapy in neuronal regeneration

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Effective Medical Devices for Treating Patellar Tendonitis 

Effective Medical Devices for Treating Patellar Tendonitis 

Shock wave therapy compared with intramedullary screw fixation for nonunion of proximal fifth metatarsal metaphyseal-diaphyseal fractures

Periodontal Cytokines Profile Under Orthodontic Force and Extracorporeal Shock Wave Stimuli in a Rat Model

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The Clinician’s Guide to Shockwave Therapy- Evidence, Safety, and Technology

The Clinician’s Guide to Shockwave Therapy: Evidence, Safety, and Technology

SoftWave OrthoGold

Best Medical Devices for Treating Wrist Tendonitis 

ESWT in skin & aesthetic indications

Cellular mechanotransduction: putting all the pieces together again

Plantar Fasciitis Medical Devices That Relieve Pain

Plantar Fasciitis Medical Devices That Relieve Pain

Immunomodulation of Osseointegration Through Extracorporeal Shock Wave Therapy

Shock waves promote spinal cord repair via TLR3

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

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Shock wave therapy alone has no impact on cancer growth

Impact of extracorporeal shock-wave therapy on the stability of temporary anchorage devices in adults: A single-center, randomized, placebo-controlled clinical trial

Substantial Biomechanical Improvement by Extracorporeal Shockwave Therapy After Surgical Repair of Rodent Chronic Rotator Cuff Tears

Mechano-transduction effect of shock waves

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Shock wave treatment reduces neuronal degeneration upon spinal cord ischemia and improves symptoms in a first-in-man trial

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​Extracorporeal shock waves as curative therapy for varicose veins? – (Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss)

SoftWave Celebrates Pro Success of Golfer Jake Peacock and Baseball Player Reid Worley, Highlighting Injury Prevention Breakthroughs

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Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury

Low-Intensity Extracorporeal Shock Wave Therapy Enhances Brain-Derived Neurotrophic Factor Expression through PERK/ATF4 Signaling Pathway

Effects of Low-Energy Shockwave Therapy on the Erectile Function and Tissue of a Diabetic Rat Model

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MTS Spark Wave Publications – Science Telegram

Lateral epicondylitis: This is still a main indication for extracorporeal shockwave therapy

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Biologic Response

The link between shockwaves and innate immunity – the main working mechanism?

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LL37 and shock waves

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IVSWT Water Bath V2.0: Standardized model for in-vitro shock wave treatment (IVSWT)

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Biological Principles – Mechanotransduction

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Biological mechanism of musculoskeletal shockwaves

Shock waves are defined as types of acoustic pressure waves that develop during sudden releases...
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​The biologic effects of SoftWaves and rationale for spine and brain therapy

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IVSWT Water Bath V2.0 Manual

The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how...
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​Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of...
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Shock wave application to cell cultures

Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that...
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Shockwave treatment enhances cell proliferation and improves wound healing

Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying...
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction

Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications...
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Latest Basic Research Abstracts

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Lohse – Busch ISMST Presentation

High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration....
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Effect of shock waves on macrophages

Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes

Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3)....
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection

Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for...
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Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3

(Johannes Holfeld, Can Tepeköylü, Radoslaw Kozaryn, Anja Urbschat, Kai Zacharowski, Michael Grimm, and Patrick Paulus)...
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Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation

(​University Hospital for Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria, 2 Division of Clinical and...
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